L-Cystine, N,N-bis[(1,1-dimethylethoxy)carbonyl]-, 1,1-dimethyl ester - Names and Identifiers
Name | N,N-DI-BOC-(L)-CYSTINE-DIMETHYL ESTER
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Synonyms | N,N-DI-BOC-(L)-CYSTINE-DIMETHYL ESTER N,N-bis(tert-butoxy)carbonyl-L-cystine dimethyl ester N,N-Bis[(1,1-diMethylethoxy)carbonyl]-L-cystine 1,1-DiMethyl Ester L-Cystine, N,N-bis[(1,1-dimethylethoxy)carbonyl]-, 1,1-dimethyl ester
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CAS | 77826-55-2
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L-Cystine, N,N-bis[(1,1-dimethylethoxy)carbonyl]-, 1,1-dimethyl ester - Physico-chemical Properties
Molecular Formula | C18H32N2O8S2
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Molar Mass | 468.58528 |
Density | 1.213±0.06 g/cm3(Predicted) |
Melting Point | 118-120°C |
Boling Point | 583.7±50.0 °C(Predicted) |
pKa | 10.33±0.46(Predicted) |
Storage Condition | Refrigerator |
L-Cystine, N,N-bis[(1,1-dimethylethoxy)carbonyl]-, 1,1-dimethyl ester - Upstream Downstream Industry
L-Cystine, N,N-bis[(1,1-dimethylethoxy)carbonyl]-, 1,1-dimethyl ester - Introduction
N,N-DI-BOC-(L)-CYSTINE-DIMETHYL (N,N-diboc-(L)-cysteine dimethyl ESTER) is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White to yellowish solid
-Molecular formula: C24H40N2O6S2
-Molecular weight: 520.73g/mol
-Melting point: 96-99 ° C
-Solubility: The compound is soluble in organic solvents such as dimethyl sulfoxide (DMSO), dimethylformamide (DMF) and diethyl ether.
Use:
N,N-DI-BOC-(L)-CYSTINE-DIMETHYL ESTER is commonly used in organic synthesis as a precursor for cysteine derivatives. Its BOC protecting group can protect the amino-containing and thiol groups of cysteine in organic synthesis to prevent unwanted reactions from occurring. In addition, the compounds are useful as cross-linking reagents in protein synthesis and in developmental biology studies.
Method:
The preparation method of
N,N-DI-BOC-(L)-CYSTINE-DIMETHYL ESTER is regular and simple, and the specific steps are as follows:
1. Cysteine and dimethylformamide (DMF) were dissolved in dimethyl sulfoxide (DMSO).
2. A solution of di-tert-butyl dikalba (Boc2O) was added to the system.
3. Stir the reaction at room temperature for several hours until the reaction is complete.
4. A saturated aqueous ammonia solution was added to neutralize the reaction system.
5. The reaction solution is evaporated to dryness by a rotary evaporator, and then the product is dissolved with a suitable organic solvent to obtain the target compound.
Safety Information:
N,N-DI-BOC-(L)-CYSTINE-DIMETHYL ESTER is an organic compound, and appropriate laboratory safety measures need to be taken during operation. The following safety operations are recommended:
-Wear appropriate personal protective equipment during operation, including lab gloves and protective glasses.
-Avoid contact with skin and eyes. In case of accidental contact, immediately flush the affected area with plenty of water and seek medical help.
-Pay attention to prevent the inhalation of dust or solution gas, and ensure that it is operated in a well-ventilated environment.
-Do not eat, drink or smoke.
-Storage should be kept in a dry, ventilated and dark place, away from fire and flammable materials.
Please note that for the use and operation of chemical reagents, it is important to follow the correct laboratory safety operations and procedures to ensure personal safety and laboratory safety.
Last Update:2024-04-10 22:29:15